holding bottle of Total Serenity supplement

Fit Healthy Momma Rating: 9/10

Total Serenity by KaraMD is a doctor-formulated supplement that contains natural ingredients shown to improve your mood, reduce stress, and promote feelings of calmness. In the hustle and bustle of today’s world, this naturally effective supplement might be exactly what you need to chill out a bit.

One glance at the recent data around stress and anxiety within our country and it’s easy to deduce that we’re more stressed out, drained, and stretched than ever before. Our bodies weren’t built for this 21st-century lifestyle that thrives on the hustle culture, dictating that we’re always “on” or else we’ll fall short.

Despite our best efforts to slow down, be present, and enter a flow state, the constant hustle and bustle of life can really put a damper on our success. Sometimes, we need a little help to calm our minds and gain clarity.

KaraMD recently launched Total Serenity for this exact purpose. This natural mood enhancement and stress relief supplement is designed to support your mental well-being while allowing you to reduce stress, minimize racing thoughts, and improve your overall mood and cognitive health.

In this review of Total Serenity, we’ll cover what’s inside, how it works, who it’s for, and ultimately, help you decide if this is the right choice for your health and wellbeing.

Quick Summary Review of Total Serenity




Key Benefits:

Contains natural ingredients shown to improve your mood, reduce stress, and promote feelings of calmness

Key Ingredients:

Ashwagandha, Panax Ginseng, Lion’s Mane, L-Theanine, Lemon Balm



Doctor Formulated:


Third-Party Tested:



KaraMD Total Serenity is made in an FDA-Registered Facility that follows the strict guidelines of the Good Manufacturing Process.



Coupon Code:

For 25% off, use code fhm25

Where to buy:

Avg. User Rating:


FHM Rating:


What is Total Serenity?

KaraMD Total Serenity product on coffee table

Total Serenity is a natural mood enhancement and stress relief supplement that’s made by KaraMD, a leader in natural health and wellness supplements. This specially formulated blend of natural herbs is designed to help support your mental well-being, leaving you feeler cool, calm, and relaxed, despite the busyness going on around you.

Total Serenity features a unique blend of herbs that, when paired together, have been shown to reduce stress, decrease racing thoughts, and improve your overall mood and cognitive health. 

All KaraMD products are formulated in the USA and manufactured in an FDA-registered facility using reliably sourced non-GMO, gluten-free, and vegan-friendly ingredients. 


  • All-natural ingredients that are clinically shown to help with overall mental health and well-being
  • Improved memory and sense of calmness
  • Helps with feelings of anxiety and depression
  • Reduces stress levels
  • Improves energy levels
  • Non-GMO, gluten-free, and vegan
  • 3rd party tested
  • Doctor formulated
  • Made in the USA
  • 90-day money-back guarantee
  • Trusted brand with a great reputation


  • As a newer product, there aren’t a ton of user reviews or testimonials quite yet
  • Some ingredients might not mix well with other medications or supplements, so be sure to speak with your doctor before starting Total Serenity

Key Ingredients Analysis

Total Serenity by KaraMD includes a special blend of powerful herbs from natural sources, all in one easy-to-take daily dose. Let’s break down the key ingredients of Total Serenity to discover how it can benefit your cognitive health.

bottles and capsules total serenity product


Used for thousands of years in traditional medicine, ashwagandha has been linked to the improvement of a variety of health conditions. Emerging research suggests that ashwagandha can help to reduce stress, increase natural energy levels, and improve focus.

Panax Ginseng

This is a natural remedy for helping to improve memory and well-being while promoting a sense of calmness. 

Lion’s Mane

This is a mushroom that’s high in anti-inflammatory and antioxidant value, allowing it to help protect you against cognitive issues like dementia while also helping you battle feelings of anxiety and depression.


As an essential amino acid, L-Theanine has been shown to improve mental health and reduce levels of stress. 

Lemon Balm

This natural herb has been shown to help induce natural relaxation and promote stress relief


This herb belongs to the Ginseng family and has been used to reduce stress hormones while also naturally boosting energy levels.

How to Take

Total Serenity is best taken with food and 8 fl oz of water. Users are encouraged to take 3 Total Serenity vegetable capsules per day.

holding total serenity capsule

Who Should Try Total Serenity?

Total Serenity by KaraMD might be a good choice for anyone who is dealing with daily stress, anxiety, and racing thoughts. For those who feel as though life is moving 100 mph around them and they aren’t able to slow down and focus, Total Serenity might be able to help provide the calm, peace, and clarity needed to get back on track and improve your overall mood and cognition.

Who Shouldn’t?

The ingredients in KaraMD’s Total Serenity formula are generally regarded as safe for use, however, it’s always best to check with your doctor before starting any new supplement or medication to ensure it’s a good fit for your circumstance and needs.

Cost and Where to Buy

Total Serenity costs $34.95 for a 30-day supply and can be purchased exclusively from KaraMD’s official website. KaraMD has a full line of health and wellness supplements and offers a discount for purchasing multiple products, so be sure to check out other options like Pure Nature, GutBio Max, and Comfort Guard X24.

total serenity products on table

Final Thoughts: Is Total Serenity by KaraMD Worth it for Stress Reduction?

If you’re dealing with stress, anxiety, and racing thoughts, Total Serenity by KaraMD is well worth trying as part of your daily wellness routine. For those of us who feel like we’re constantly getting caught up in the rat race and hustle culture that has become our everyday, a safe, effective, and natural supplement like Total Serenity might be the very welcomed change we need to slow down, ease our stress, and start feeling calmer and at peace.

All KaraMD products are thoughtfully and responsibly sourced and formulated by a renowned doctor with years of experience in the medical field, giving you peace of mind that you’re purchasing a product that’s been designed to work efficiently and effectively. Of course, there’s no magic pill for stress and anxiety in your life, you will also need to implement some stress relief tactics like meditation, deep breathing, and maybe even a tweak of your current schedule to help you slow down. However, adding a supplement like Total Serenity might be able to help get you there a little faster.

capsules - total serenity product
About the Author
Tami Smith, CPT, Nutritionist

Tami Smith is a certified Nutritionist and an ACE certified fitness trainer, specializing in pre and post-natal fitness. She studied business and earned her bachelor's degree in Business Economics. Tami is a mom of two and women's health advocate. Her passion is to help people live a fit, healthy life through proper nutrition and exercise!

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